Accutane, Isotretinoin
Buy Accutane to treat severe cystic acne vulgaris, hidradenitis suppurativa, severe acne rosacea, and xeroderma pigmentosum. It is usually taken at a dosage of 0.5 mg per kg body weight per day, divided into two doses daily. Accutane is taken orally, with or without food.
To read more about Accutane side effects, Accutane dosage, and for more useful information about Accutane (isotretinoin), please click the product information link below.
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Other name(s): Roaccutane, Clarus, Oratane, Isotane, Izotek, Sotret |
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Often prescribed for acne vulgaris, acne rosacea, hidradenitis suppurativa, xeroderma pigmentosum |
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Accutane, IsotretinoinChemical NamesIsotretinoin
Isotretinoin. Allergy sufferers: the caplets contain parabens, soya, peanut, and sorbitol.
Indications
Accutane is indicated in the treatment of severe cystic acne vulgaris, severe acne roscacea, xeroderma pigmentosum and hidradenitis suppurativa.
How It Works
Accutane's exact mechanism of action is unknown, but it is believed to involve the increase of neutrophil-gelatinase associated lipocalin (NGAL) production in the skin, which reduces sebum production, thereby reducing sebum-induced or sebum-aggravated acne and other skin conditions.
Dosage
Caplets: 5 mg, 10 mg, 20 mg, 30 mg
In treating acne vulgaris, Accutane is usually taken in high dosages, typically at 0.5 mg per kilogram body weight per day. This amount is divided into two doses per day, taken orally with food, for a period of 4 to 6 months. Lower dosages of 10 mg to 20 mg per day have also been shown to be effective, but can increase the likelihood of acne relapse.
Precautions
Consult a doctor before taking Accutane if you are pregnant or breastfeeding, if you are allergic to any of its ingredients, or if you have (or have a family history of) diabetes, high blood fats, psychiatric disorders, liver disease, pancreatitis, or bone loss conditions such as osteoporosis.
Do not donate blood while taking Accutane, nor for one month after cessation of an Accutane regimen.
Drug Interactions
Consult a doctor before taking Accutane if you are also taking any of the following: vitamin A or related drugs (such as etretinate or tretinoin), tetracycline antibiotics (especially minocycline), drugs which cause bone loss (such phenytoin, corticosteroids such as prednisone), St John's wort, or any other drug that can decrease the effectiveness of birth control pills.
Adverse/Side Effects
Minor side effects of Accutane may include: dry lips and mouth, minor swelling of the eyelids or lips, crusty skin, nosebleeds, indigestion, or thinning of the hair.
Severe side effects of Accutane are rare, but may include: mental or mood changes, tingling skin, pancreatitis, severe headache, tinnitus, fever, muscle or joint pain, altered vision, dark urine or yellowing eyes and skin, severe diarrhea, or rectal bleeding.
Accutane can cause increased epidermal photosensitivity - avoid prolonged exposure to sunlight or sun lamps while taking Accutane.
Consult a doctor if you experience any of the side effects while taking Accutane.
Overdose
Symptoms of Accutane overdose may include vomiting, stomach pain, facial flushing, headache, dizziness, and loss of balance. Consult a doctor or visit a hospital immediately if you experience overdose symptoms.
Storage Instructions
Accutane should be stored between 59 and 86 degrees F (between 15 and 30 degrees C) and kept away from moisture and sunlight. Do not store in the bathroom, or any place where children might gain access to it.
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