Buy Asendin, amoxapineBuy Asendin to treat symptoms of depression in patients with neurotic or reactive depressive disorders as well as endogenous and psychotic depressions. Its initial dosage is 50 mg two or three times daily. Depending upon your tolerance, dosage may be increased to 100 mg two or three times daily by the end of the first week. The proper maintenace dosage is the lowest dose that will treat symptoms.Contraindications: Before taking Asendin tell your doctor if you are pregnant or breastfeeding, if you are allergic to any of its ingredients, if you are taking any other medications (especially anticholinergics (such as atropine or belladonna alkaloids), antihypertensives, levodopa, motion sickness medications, nasal decongestants, psychiatric drugs, stimulants, thyroid medications, or MAOIs), or if you have or have a history of heart disease, heart attack, strokes, seizures, kidney disease, schizophrenia, diabetes, glaucoma, or problems with urination. To read more about Asendin, amoxapine side effects, Asendin, amoxapine dosage, and for more useful information about Asendin, amoxapine, please click the product information link below. |
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Other name(s): Asendis, Defanyl |
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Often prescribed for major depression, anxiety disorder, bipolar disorder, panic disorder |
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Asendin, amoxapineChemical Namesamoxapine Ingredients Active ingredients: amoxapine Non-active ingredients: dibasic calcium phosphate, magnesium stearate, starch (corn), and stearic acid. Indications Asendin is indicated in the treatment of major depression, anxiety disorder, panic disorder, and bipolar disorder. Patients who have failed to respond satisfactorily to other antidepressants may show response to amoxapine. How It Works Amoxapine inhibits the neuronal re-uptake of noradrenaline and serotonin (5-HT2) in the CNS. It also blocks the response of dopamine receptors to dopamine. Dosage Oral tablets (50 mg, 100 mg) Usual starting dosage is 50 mg two or three times daily. Depending upon tolerance, dosage may be increased to 100 mg two or three times daily by the end of the first week. (Initial dosage of 300 mg daily may be given, but notable sedation may occur in some patients during the first few days of therapy at this level. Effective dosage is 200 to 300 mg daily. Three weeks constitutes an adequate period of trial providing dosage has reached 300 mg daily (or lower level of tolerance) for at least two weeks. If no response is seen at 300 mg, dosage may be increased, depending upon tolerance, up to 400 mg daily. The recommended maintenance dosage of amoxapine is the lowest dose that will maintain remission. Since for each person this is different consult doctor. In elderly patients, lower dosages are recommended for these patients. Recommended starting dosage of amoxapine is 25 mg two or three times daily. If no intolerance is observed, dosage may be increased by the end of the first week to 50 mg two or three times daily. Although 100 to 150 mg daily may be adequate for many elderly patients, some may require higher dosage. Do not use this medication if you are allergic to amoxapine, or if you have recently had a heart attack. When it is desired to replace a monoamine oxidase inhibitor with amoxapine, a minimum of 14 days should be allowed to elapse after the former is discontinued. You may have thoughts about suicide when you first start taking an antidepressant, especially if you are younger than 24 years old. Your doctor will need to check you at regular visits for at least the first 12 weeks of treatment. Before taking Asendin tell your doctor if you have a history of heart disease, heart attack, strokes, seizures, kidney disease, schizophrenia, diabetes, glaucoma, problems with urination. Amoxapine, like many other systemic drugs, is excreted in human milk. Because effects of the drug on infants are unknown, caution should be exercised when amoxapine is administered to nursing women. Drug Interactions Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: anticholinergics (e.g., atropine, belladonna alkaloids), certain drugs for high blood pressure (e.g., clonidine, guanethidine, reserpine), levodopa, drugs for motion sickness (e.g., meclizine), nasal decongestants (e.g., phenylephrine), psychiatric drugs (e.g., lithium, antipsychotics, antidepressants), stimulants (e.g., epinephrine, amphetamine), thyroid supplements. If you have been taking fluoxetine, wait at least 5 weeks after stopping fluoxetine before starting this medication. Do not take this medication if you are taking MAO inhibitors (e.g., furazolidone, isocarboxazid, linezolid, moclobemide, phenelzine, procarbazine, rasagiline, selegiline, tranylcypromine) or have used MAO inhibitors in the past 2 weeks. In some cases a serious, possibly fatal drug interaction may occur. Adverse/Side Effects Most common: dry mouth, constipation, blurred vision. Uncommon: anxiety , insomnia, restlessness, nervousness, palpitations, tremors, confusion, excitement, nightmares, ataxia, alterations in EEG patterns, edema, skin rash, nausea, dizziness, headache, fatigue, weakness, excessive appetite, increased perspiration. Rare: anticholinergic disturbances of accommodation, mydriasis, delayed micturition, urinary retention, nasal stuffiness, hypotension, syncope, tachycardia, drug fever, urticaria, photosensitization, pruritus, vasculitis, hepatitis, tingling, paresthesias of the extremities, tinnitus, disorientation, seizures, hypomania, numbness, incoordination, disturbed concentration, hyperthermia, extrapyramidal symptoms, tardive dyskinesia, nerolepptic malignant syndrome, leukopenia, agranulocytosis, epigastric distress, vomiting, flatulence, abdominal pain, peculiar taste, diarrhea, increased or decreased libido, impotence, menstrual irregularity, breast enlargement and galactorrhea in the female, syndrome of inappropriate antidiuretic hormone secretion, lacrimation, weight gain or loss, altered liver function, painful ejaculation. Very Rare: paralytic ileus, atrial arrhythmias (including atrial fibrillation), myocardial infarction, stroke, heart block, hallucinations, thrombocytopenia, eosinophilia, purpura, petechiae, parotid swelling, change in blood glucose levels, pancreatitis, hepatitis, jaundice, urinary frequency, testicular swelling, anorexia, sublingual adenitis, dilation of the urinary tract, delusions, stomatitis, black tongue, gynecosmastia. Call your doctor at once if you have any new or worsening symptoms such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself. Overdose If overdose is suspected, contact your local poison control center or emergency room immediately. Storage Instructions Store at room temperature between 59-86 degrees F (15-30 degrees C) away from light and moisture. Do not store in the bathroom. Keep all medicines away from children and pets. |