Buy Hyzaar (losartan and hydrochlorothiazide) to treat hypertension and high blood pressure. Initial dosage of Hyzaar is one pill per day, which can be increased to a maximum of two per day if necessary.

 

Contraindications: Do not take Hyzaar if you are pregnant or breast-feeding, or if you are allergic to any of its ingredients. Consult a doctor if you are taking any other medications (especially other diuretics "water pills" or other blood pressure medications, lithium, pain killers, cholestyramine or colestipol, steroids, NSAIDs (non-steroidal anti-inflammatory drugs) such as aspirin, ibuprofen, diclofenac, indomethacin, naproxen, piroxicam, nabumetone, etodolac, and others, or insulin and diabetes medicine), or if you have a history of kidney disease, liver disease, congestive heart failure, asthma, gout, lupus, diabetes, or an allergy to sulfa drugs.

Chemical Name

losartan-hydrochlorothiazide

 

Ingredients

Active Ingredients: losartan and hydrochlorothiazide

 

Non-Active Ingredients: microcrystalline cellulose, lactose hydrous, pregelatinized starch, magnesium stearate, hydroxypropyl cellulose, hypromellose, and titanium dioxide.

 

Indications

Hyzaar is used to treat hypertension, high blood pressure, and congestive heart failure.

 

How It Works

Hydrochlorothiazide is a thiazide diuretic "water pill," which helps prevent the body from absorbing too much salt, which causes fluid retention. Losartan is an angiotensin II receptor antagonist. Losartan keeps blood vessels from narrowing, which improves blood flow and lowers blood pressure. The combination of hydrochlorothiazide and losartan is used to treat hypertension (high blood pressure).

 

Dosage

Tablets (100mg / 25mg or 50mg / 12.5mg) of losartan / hydrochlorothiazide

 

The usual dosage range of losartan is 50 to 100mg per day administered in a single dose or two divided doses. Hydrochlorothiazide is taken in doses of 12.5 to 50mg daily. Hyzaar combines the two medications in a 4:1 ratio. Initial dosage should be one Hyzaar tablet per day (of the 50mg/ 12.5mg tablet), if necessary this can be increased to two tablets per day or a single dose of the larger tablet (but not more).

 

Precautions

Hyzaar is contraindicated in pregnant women and women who are breast-feeding. You should not use this medication if you are allergic to Hyzaar, any of its components or if you are suffering from dehydration or unable to urinate.

 

Before taking Hyzaar, (hydrochlorothiazide and losartan), tell your doctor if you have a history of kidney disease (or are on dialysis), liver disease, low or high blood levels of potassium, congestive heart failure, asthma, gout, lupus, diabetes, or an allergy to sulfa drugs.

Some things may lower your blood pressure too much, including vomiting, diarrhea, heavy sweating, heart disease, dialysis, a low-salt diet, or taking other diuretics (water pills). Follow your doctor's instructions about amount of liquids you should drink as well as the types of liquids you should drink while taking hydrochlorothiazide and losartan. Tell your doctor if you are prone to diarrhea or vomiting or if you have a condition causing either of these. Do not use salt substitutes and do not take potassium supplements unless your doctor has told you to do so.

Avoid losing excess amounts of water, becoming overheated, dehydrated, exercising excessively or in hot weather. In some cases, drinking too much liquid can be as unsafe as not drinking enough. All patients should be cautioned that excessive sweating and dehydration may lead to a fall in blood pressure because of the decrease in fluid volume. Other causes of volume depletion such as vomiting or diarrhea may also lead to a fall in blood pressure; patients should be advised to consult with the physician.

 

Avoid getting up too fast, which may make you feel dizzy. Avoid drinking alcohol, which can increase some of the side effects of hydrochlorothiazide and losartan.

 

This medicine may cause harm to an unborn baby and has been known to cause birth defects. Before taking Hyzaar, tell your doctor if you are pregnant or plan to become pregnant during treatment. Hyzaar passes into breast milk and may causes harm to a nursing baby. Tell your doctor right away if you become pregnant. You should not be breast feeding on this medication. 

 

Drug Interactions

Consult a doctor before taking Hyzaar, if you are taking any of the following: other diuretics "water pills" or other blood pressure medications, steroids (prednisone or others), lithium, digoxin, celecoxib, cholestyramine or colestipol, steroids, NSAIDs (non-steroidal anti-inflammatory drugs) such as aspirin, ibuprofen, diclofenac, indomethacin, naproxen, piroxicam, nabumetone, etodolac, and others, rifampin, a barbiturate such as phenobarbital or others or insulin and diabetes medicine taken orally.

 

Avoid other medicines that can cause light-headed and drowsiness (such as cold medicine, narcotic pain medication, muscle relaxers, and medicine for seizures, depression or anxiety). These can add to the side effects of Hydrochlorothiazide and losartan. Tell your doctor if you regularly use any of these medicines, or any other blood pressure medications. Do not use salt substitutes and do not take potassium supplements unless your doctor has told you to do so.

 

 Before using this Hyzaar, tell your doctor or pharmacist about all prescription and non-prescription medications, including herbal products, minerals and vitamins you may be taking. Other medications may affect how Hyzaar works or may cause other unforeseen complications.

Drug Interactions

Consult a doctor before taking Hyzaar, if you are taking any of the following: other diuretics "water pills" or other blood pressure medications, steroids (prednisone or others), lithium, digoxin, celecoxib, cholestyramine or colestipol, steroids, NSAIDs (non-steroidal anti-inflammatory drugs) such as aspirin, ibuprofen, diclofenac, indomethacin, naproxen, piroxicam, nabumetone, etodolac, and others, rifampin, a barbiturate such as phenobarbital or others or insulin and diabetes medicine taken orally.

 

Avoid other medicines that can cause light-headed and drowsiness (such as cold medicine, narcotic pain medication, muscle relaxers, and medicine for seizures, depression or anxiety). These can add to the side effects of Hydrochlorothiazide and losartan. Tell your doctor if you regularly use any of these medicines, or any other blood pressure medications. Do not use salt substitutes and do not take potassium supplements unless your doctor has told you to do so.

 

 Before using this Hyzaar, tell your doctor or pharmacist about all prescription and non-prescription medications, including herbal products, minerals and vitamins you may be taking. Other medications may affect how Hyzaar works or may cause other unforeseen complications.

 

Adverse/Side Effects

It is common that Hyzaar causes the following minor side effects: stomach pain, back pain, dry cough, dizziness, headache, tired feeling, diarrhea, constipation, upset stomach, mild skin rash, or increased sweating. If these side effects persist or become overly bothersome, contact your doctor or health-care professional. 

 

If you experience any of these less common but serious side effects contact you doctor immediately: high potassium (slow heart rate, weak pulse, muscle weakness, tingly feeling), low potassium (confusion, uneven heart rate, extreme thirst, increased urination, leg discomfort, muscle weakness or limp feeling), dry mouth, thirst, nausea, vomiting, fainting, feeling weak, drowsy, restless, light-headedness, a red, blistering, peeling skin rash, pale skin, easy bruising or bleeding, seizures (convulsions), jaundice (yellowing of the skin or eyes), urinating less than usual or not at all, swelling, weight gain, feeling short of breath, fever, chills, body aches, and flu symptoms. 

 

A very serious allergic reaction to this drug is rare. Get emergency medical help if you have any of these signs of an allergic reaction: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, or trouble breathing. This may not be a complete list of side effects and may be subject to change, consult with your doctor or pharmacist if you are experiencing any worrisome side effects.

 

Overdose

If you suspect overdose, contact your local poison control center or emergency room immediately. Symptoms of overdose include feeling light-headed, fast or slow heartbeat, or fainting.

 

Storage Instructions

Store at room temperature, away from moisture and light, and out of reach of children and pets.