 Home / Cholesterol Lowering / Caduet, amlodipine and atrovastatin |
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Buy Caduet, amlodipine and atrovastatin Buy Caduet to treat high cholesterol (hypercholesterolemia), high blood pressure (hypertension), high blood fat (hyperlipidemia), angina and coronary artery disease. Caduet is also indicated in the prevention of cardiovascular disease, especially myocardial infarction and stroke. The usual dosage of Caduet is one to two tablets taken once daily.Contraindications: Consult a doctor before taking Caduet if you are pregnant or breastfeeding, if you are allergic to any of its ingredients, if you are taking any other medications (especially other statins (including lovastatin, pravastatin, simvastatin, fluvastatin and rosuvastatin), azole antifungals (such as itraconazole and ketoconazole), macrolide antibiotics (such as clarithromycin, erythromycin and troleandomycin), mibefradil, nefazodone, telithromycin, fibrates (such as fenofibrate and gemfibrozil), niacin, birth control pills, intravenous calcium, nitroglycerin or other chest pain medications, clopidogrel, digoxin, any other antihypertensives, HIV protease inhibitors (such as indinavir and ritonavir), amiodarone, cyclosporine, diltiazem, verapamil, rifampin St John’s wort, or carbamazepine.), or if you have a history of liver disease, heart disease, kidney disease, hypothyroidism, or alcohol abuse. To read more about Caduet, amlodipine and atrovastatin side effects, Caduet, amlodipine and atrovastatin dosage, and for more useful information about Caduet, amlodipine and atrovastatin, please click the product information link below.  PRODUCT INFORMATION |
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Other name(s): Envacar |
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Often prescribed for high cholesterol, hypercholesterolemia, high blood pressure, hypertension |
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READ MORE ABOUT CHOLESTEROL LOWERING
Caduet, amlodipine and atrovastatinChemical Namesamlodipine/atorvastatin Ingredients Active Ingredients: amlodipine/atorvastatin Non-Active Ingredients: calcium carbonate, croscarmellose sodium, microcrystalline cellulose, pregelatinized starch, polysorbate 80, hydroxypropyl cellulose, purified water, colloidal silicon dioxide (anhydrous), magnesium stearate, Opadry® II White 85F28751 (polyvinyl alcohol, titanium dioxide, PEG 3000 and talc) or Opadry® II Blue 85F10919 (polyvinyl alcohol, titanium dioxide, PEG 3000, talc and FD&C blue #2). Combinations of atorvastatin with 2.5 mg and 5 mg amlodipine are film coated white, and combinations of atorvastatin with 10 mg amlodipine are film coated blue. Indications Caduet is indicated in the treatment of high cholesterol (hypercholesterolemia), high blood pressure (hypertension), high blood fat (hyperlipidemia), angina and coronary artery disease. Caduet is also indicated in the prevention of cardiovascular disease, especially myocardial infarction and stroke. How It Works Caduet combines amlodipine, a calcium channel blocker, with atorvastatin, a cholesterol-lowering medication. Calcium channel blockers decrease the force of contraction of the heart, lowering its oxygen demands and reducing hypertension. Statins inhibit the enzyme responsible for cholesterol synthesis in the liver, lowering blood cholesterol levels; they also increase the number of low density lipoprotein (LDL) receptors, lowering blood lipid levels. Dosage Available tablet sizes (amlodipine/atorvastatin): 5mg/10mg The usual dosage of Caduet is one to two tablets taken once daily, depending on the severity of the condition and the patient’s response. Hypercholesterolimia is usually treated with Caduet in conjunction with another antihypercholesterolimic. What follows is more specific information on the indications of amlodipine and atorvastatin in the treatment of their approved conditions: Hypertension: The usual initial antihypertensive oral dose of amlodipine is 5 mg once daily with a maximum dose of 10 mg once daily. Small, fragile, or elderly individuals, or patients with hepatic insufficiency may be started on 2.5 mg once daily and this dose may be used when adding amlodipine to other antihypertensive therapy. Dosage should be adjusted according to each patient’s need. Angina: The recommended dose of amlodipine for chronic stable or vasospastic angina is 5-10 mg, with the lower dose suggested in the elderly and in patients with hepatic insufficiency. Most patients will require 10 mg for adequate effect. Coronary artery disease: The recommended dose range of amlodipine for patients with coronary artery disease is 5-10 mg once daily. In clinical studies the majority of patients required 10 mg. Hypercholesterolimia: The dosage of atorvastatin in patients with homozygous FH is 10 to 80 mg daily. Atorvastatin should be used as an adjunct to other lipid-lowering treatments (e.g., LDL apheresis) in these patients or if such treatments are unavailable. Note: a 2.5/80 mg Caduet tablet is not available. In patients taking cyclosporine, therapy should be limited to atorvastatin 10 mg once daily. In patients taking clarithromycin, itraconazole or in patients with HIV taking a combination of ritonavir plus saquinavir or lopinavir plus ritonavir, for doses of atorvastatin exceeding 20 mg, appropriate clinical assessment is recommended to ensure that the lowest dose necessary of atorvastatin is employed. Consult a doctor before taking Caduet if you are pregnant or breastfeeding, if you are allergic to any of its ingredients, or if you have or have a history of liver disease, heart disease, kidney disease, hypothyroidism, or alcohol abuse. Do not stop taking this medication without consulting a doctor, especially if you are due to have major surgery or if you are suffering from serious illness or trauma, including sepsis, severe hypotension, uncontrolled seizures, or severe metabolic, endocrine or electrolyte disorders. This drug may make you dizzy; use caution when using heavy machinery or driving while taking this medication. This drug is known to cause fetal harm. Pregnant women should avoid using this medication if at all possible. Drug Interactions Consult a doctor before taking Caduet if you are taking other statins (including lovastatin, pravastatin, simvastatin, fluvastatin and rosuvastatin), azole antifungals (such as itraconazole and ketoconazole), macrolide antibiotics (such as clarithromycin, erythromycin and troleandomycin), mibefradil, nefazodone, telithromycin, fibrates (such as fenofibrate and gemfibrozil), niacin, birth control pills, intravenous calcium, nitroglycerin or other chest pain medications, clopidogrel, digoxin, any other antihypertensives, HIV protease inhibitors (such as indinavir and ritonavir), amiodarone, cyclosporine, diltiazem, verapamil, rifampin St John’s wort, or carbamazepine. Adverse/Side Effects Headache, dizziness, drowsiness, flushing, diarrhea, stomach/abdominal pain, weakness, or joint pain may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. This drug may infrequently cause muscle damage (which can rarely lead to a very serious, possibly fatal, condition called rhabdomyolysis). Seek immediate medical attention if you develop: muscle pain/tenderness/weakness (especially with fever or unusual tiredness). Tell your doctor immediately if any of these highly unlikely but very serious side effects occur: irregular heartbeat, swelling of the hands or feet, worsening chest pain (attacks are more frequent, more severe, or last longer), yellowing of the eyes or skin, dark urine, severe fatigue, severe stomach/abdominal pain, persistent nausea, change in the amount of urine. Overdose Symptoms of Caduet overdose are unknown, but are likely to include dizziness, fainting, fast heartbeat, and other signs of severe hypotension. If you suspect overdose, contact your local poison control center or emergency room immediately. Storage Instructions Store at room temperature, away from moisture and light, and out of reach of children and pets. |
