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 Buy Januvia, sitagliptinBuy Januvia to treat type 2 diabetes. It is a dipeptidyl peptidase-4 inhibitor-class antidiabetic that is taken orally, with or without food, at a usual dosage of 100 mg per day. PRODUCT INFORMATION |
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Other name(s): Janumet, Xelevia, MK-0431 |
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Often prescribed for type 2 diabetes |
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READ MORE ABOUT DIABETES
Januvia, sitagliptinOther names: Janumet, Xelevia, MK-0431
1. What Is Januvia (Janumet, Xelevia, MK-0431, Sitagliptin)
Januvia is a member of a class of medicines you take by mouth called DPP-4 inhibitors (dipeptidyl peptidase-4 inhibitors) that lowers blood sugar levels in patients with type 2 diabetes mellitus. Type 2 diabetes is also called non-insulin-dependent diabetes mellitus, or NIDDM.
Januvia helps to improve the levels of insulin after a meal and decreases the amount of sugar made by the body. It is unlikely to cause low blood sugar because it does not work when your blood sugar is low. However, when Januvia is used in combination with a sulphonylurea medicine, low blood sugar (hypoglycemia) can occur.
Your doctor has prescribed Januvia to help lower your blood sugar, which is too high because of your type 2 diabetes. Januvia is used in combination with certain other medicines that lower blood sugar, which you will already be taking for your diabetes together with a food and exercise plan. Your doctor is now prescribing Januvia as an additional medicine to help control your blood sugar.
What is type 2 diabetes?
Type 2 diabetes is a condition in which your body does not make enough insulin, and the insulin that your body produces does not work as well as it should. Your body can also make too much sugar. When this happens, sugar (glucose) builds up in the blood. This can lead to serious medical problems like heart disease, kidney disease, blindness and amputation.
2. Before You Take Januvia (Janumet, Xelevia, MK-0431, Sitagliptin)
Do not take Januvia
- if you are allergic (hypersensitive) to sitagliptin or any of the other ingredients of Januvia.
Take special care with Januvia
Tell your doctor if you have or have had:
- type 1 diabetes
- diabetic ketoacidosis (a complication of diabetes with high blood sugar, rapid weight loss, nausea or vomiting)
- any kidney problems, or any past or present medical problems. If you have kidney problems, Januvia may not be the right medicine for you.
- an allergic reaction to Januvia.
If you are taking a sulphonylurea with Januvia you may experience low blood sugar. Your doctor may reduce the dose of your medication that contains sulphonylurea.
Taking other medicines
Januvia (Janumet, Xelevia, MK-0431, Sitagliptin) may be taken with most medicines. Tell your doctor or pharmacist about all the medicines you take or have recently taken. This includes prescription and non-prescription medicines, and herbal supplements.
Taking Januvia with food and drink
You can take Januvia with or without food and drink.
Pregnancy and breastfeeding
Women who are pregnant or plan to become pregnant should consult their doctor before taking Januvia. You should not use Januvia during pregnancy. It is not known if Januvia passes into breast milk. You should not use Januvia if you are breast-feeding or plan to breastfeed.
Driving and using machines
Januvia is not expected to interfere with your ability to drive or to use machines. However, when driving or operating machinery, it should be taken into account that dizziness and drowsiness has been reported.
3. How To Take Januvia (Janumet, Xelevia, MK-0431, Sitagliptin)
Always take Januvia exactly as your doctor has told you. You should check with your doctor or pharmacist if you are not sure.
The usual dose is:
- one 100 mg film-coated tablet
- once a day
- by mouth
Your doctor will prescribe Januvia along with certain other medicines that lower blood sugar.
Continue to take Januvia as long as your doctor prescribes it so you can continue to help control your blood sugar.
Diet and exercise can help your body use its blood sugar better. It is important to stay on the diet, exercise and weight loss program recommended by your doctor while taking Januvia.
If you take more Januvia than you should
If you take more than the prescribed dosage of Januvia, contact your doctor immediately.
If you forget to take Januvia
If you miss a dose, take it as soon as you remember. If you do not remember until it is time for your next dose, skip the missed dose and go back to your regular schedule. Do not take a double dose of Januvia.
4. Possible Side Effects
Like all medicines, Januvia may cause side effects, although not everybody gets them.
Very common side effects (more than 1 per 10 patients)
Common side effects (less than 1 per 10 but more than 1 per 100 patients)
Uncommon side effects (less than 1 per 100 but more than 1 per 1000 patients)
Some patients have experienced the following side effects after adding sitagliptin to metformin (Januvia, Glucophage):
Common: nausea
Uncommon: weight loss, loss of appetite, abdominal pain, diarrhea, low blood sugar, drowsiness.
Some patients have experienced stomach discomfort when starting the combination of sitagliptin and metformin together.
Some patients have experienced the following side effects while taking Januvia in combination with a sulphonylurea:
Very common: low blood sugar
Some patients have experienced the following side effects while taking Januvia in combination with a sulphonylurea and metformin:
Very common: low blood sugar
Common: constipation
Some patients have experienced the following side effects while taking Januvia and pioglitazone:
Common: low blood sugar and flatulence. In addition, some patients have reported foot swelling while taking Januvia and pioglitazone. These side effects may be seen with sitagliptin and any glitazone (e.g., rosiglitazone).
Some patients have experienced the following side effects while taking Januvia alone:
Common: low blood sugar, headache
Uncommon: dizziness, constipation
In addition, some patients have reported the following side effects while taking Januvia:
Common: upper respiratory infection, stuffy or runny nose and sore throat, osteoarthritis, arm or leg pain.
During post marketing experience the following side effects have also been reported (frequency not known): allergic reactions, including skin rash, hives, and swelling of the face, lips, tongue, and throat that may cause difficulty in breathing or swallowing. These allergic reactions may require immediate treatment.
If any of the side effects gets serious, or if you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist.
5. How To Store Januvia (Janumet, Xelevia, MK-0431, Sitagliptin)
Keep out of the reach and sight of children.
Do not use Januvia after the expiry date which is stated on the blister and the carton. The expiry date refers to the last day of that month.
This medicinal product does not require any special storage conditions.
Medicines should not be disposed of via water or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.
6. Composition of Januvia
- The active substance is sitagliptin. Each film-coated tablet contains sitagliptin phosphate monohydrate, equivalent to 100 mg. sitagliptin.
- The other ingredients are: microcrystalline cellulose (E460), calcium hydrogen phosphate, anhydrous (E341), croscarmellose sodium (E468), magnesium stearate (E470b), and sodium stearyl fumarate. The tablet film coating contains: polyvinyl alcohol, macrogol 3350, talc (E553b), titanium dioxide (E171), red iron oxide (E172), and yellow iron oxide (E172).
All medications must be kept out of the reach and sight of children.
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