 Home / Heart and Vascular / Betapace, sotalol |
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Buy Betapace, sotalol Buy Betapace to treat cardiac arrhythmias and hypertension.Contraindications: Consult a doctor before taking Betapace if you are pregnant or breastfeeding, if you are allergic to any of its ingredients, if you are taking any other medications (especially blood pressure medications [e.g.: clonidine], anti-diabetic drugs, calcium channel blockers [e.g., verapamil, diltiazem], antacids, St John's wort, arbutamine, aspirin/NSAIDS [e.g., ibuprofen, naproxen], or any drugs that affect the heart rhythm, such as dofetilide, pimozide, quinidine, procainamide, sparfloxacin, and diuretics), or if you have a history of kidney disease, heart disease, lung disease, asthma, emphysema, thyroid disease, diabetes, and any allergies. To read more about Betapace, sotalol side effects, Betapace, sotalol dosage, and for more useful information about Betapace, sotalol, please click the product information link below.  PRODUCT INFORMATION |
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Other name(s): Sotalex |
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Often prescribed for arrhythmias, tachycardia, hypertension, high blood pressure |
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READ MORE ABOUT HEART AND VASCULAR
Betapace, sotalolChemical Namessotalol Ingredients Active Ingredients: sotalol Non-Active Ingredients: microcrystalline cellulose, lactose, starch, stearic acid, magnesium stearate, colloidal silicon dioxide, and FD&C blue color #2 (aluminum lake, conc.). Indications Betapace is indicated for the treatment of documented ventricular arrhythmias, such as sustained ventricular tachycardia, that in the judgment of the physician are life-threatening. How It Works Sotalol hydrochloride is a racemic mixture of d- and l-sotalol. Both isomers have similar Class III antiarrhythmic effects, while the l-isomer is responsible for virtually all of the beta-blocking activity. Dosage Available tablet sizes: 40 mg, 80 mg, 160 mg Adult: The recommended initial dose is 80 mg twice daily. This dose may be increased, if necessary, after appropriate evaluation to 240 or 320 mg/day (120-160 mg twice daily). In most patients, a therapeutic response is obtained at a total daily dose of 160 to 320 mg/day, given in two or three divided doses. Some patients with life-threatening refractory ventricular arrhythmias may require doses as high as 480-640 mg/day; however, these doses should only be prescribed when the potential benefit outweighs the increased risk of adverse events Renal impairment: Because sotalol is excreted predominantly in urine and its terminal elimination half-life is prolonged in conditions of renal impairment, the dosing interval (time between divided doses) of sotalol should be modified. Dose escalations in renal impairment should be done after administration of at least 5-6 doses at appropriate intervals. Talk to your doctor for correct dosage. Children: For children aged about 2 years and older, with normal renal function, doses normalized for body surface area are appropriate for both initial and incremental dosing. For initiation of treatment, 30 mg/m2 three times a day (90 mg/m2 total daily dose) is approximately equivalent to the initial 160 mg total daily dose for adults. Subsequent titration to a maximum of 60 mg/m2 (approximately equivalent to the 360 mg total daily dose for adults) can then occur. Titration should be guided by clinical response, heart rate and QTc, with increased dosing being preferably carried out in-hospital. For a child aged 20 months, the dosing suggested for children with normal renal function aged 2 years or greater should be multiplied by about 0.97; the initial starting dose would be (30 X 0.97)=29.1 mg/m2, administered three times daily. For a child aged 1 month, the starting dose should be multiplied by 0.68; the initial starting dose would be (30 X 0.68)=20 mg/m2, administered three times daily. For a child aged about 1 week, the initial starting dose should be multiplied by 0.3; the starting dose would be (30 X 0.3)=9 mg/m2. Similar calculations should be made for increased doses as titration proceeds. Since the half-life of sotalol decreases with decreasing age (below about 2 years), time to steady-state will also increase. Renal impairment: The use of sotalol hydrochloride in children with renal impairment has not been investigated. Consult your doctor before taking Betapace if you are pregnant or breastfeeding, if you are allergic to any of its ingredients, or if you have (or have a history of) kidney disease, heart disease, lung disease, asthma, emphysema, thyroid disease, diabetes, and any allergies. If you have angina or have had heart problems, do not suddenly stop using this medication without first consulting your doctor. If your doctor decides you should no longer use this medication, you must stop this medication gradually according to your doctor's instructions. Drug Interactions Talk with your doctor before taking if you are on any of the following medications: blood pressure medications (e.g., clonidine), anti-diabetic drugs, calcium channel blockers (e.g., verapamil, diltiazem), antacids, St John's wort, arbutamine, aspirin/NSAIDS (e.g., ibuprofen, naproxen), or any drugs that affect the heart rhythm, such as dofetilide, pimozide, quinidine, procainamide, sparfloxacin, and diuretics. Do not take any over-the-counter medication for allergies or cough or colds without consulting your doctor or pharmacist first. Adverse/Side Effects Serious side effects: Torsade de Pointes and new ventricular arrhythmias. Drowsiness, dizziness, lightheadedness, headache, stomach upset, or blurred vision may occur the first several days as your body adjusts to the medication. Other common side effects reported include cough, decreased sexual desire, trouble sleeping, reduced concentration, altered taste, dry skin, or muscle aches. If any of these effects continue or worsen, notify your doctor immediately. Notify your doctor if you develop: chest pain, skin rash, sore throat, breathing trouble, mental confusion, trouble urinating, easy bruising or bleeding. Tell your doctor immediately if any of these highly unlikely but very serious side effects occur: fainting, irregular heartbeat. To avoid dizziness and lightheadedness when rising from a seated or lying position, get up slowly. Also limit your intake of alcoholic beverages which will aggravate these effects. Warnings Since this medication can cause irregular heartbeats, it should only be started while you are in a hospital where your condition can be closely monitored (e.g., EKG) for at least 3 days. If your dosage is being increased, close monitoring is advised. Do not switch brands of this medication without checking with your doctor. Overdose Symptoms of overdose include severe vomiting, unconsciousness, or seizures. If you suspect overdose, contact your local poison control center or emergency room immediately. Storage Instructions Store at room temperature between 59 and 86 degrees F (15 to 30 degrees C) away from heat and light. Do not store in the bathroom. |
