![]() Buy Sandomigran, pizotifenBuy Sandomigran to prevent migraine headaches. It comes in 0.5 mg tablet form, and is taken orally – initially just once a day, but this is gradually increased to 3 times daily, up to a maximum of 6 mg per day. |
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Often prescribed for migraines |
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Sandomigran, pizotifenWhat is this drug used for?
Pizotifen (Sandomigran) is used for the prevention of migraine headaches. It is not used to treat headaches once they have started. It is not known exactly how this medication works, but it is thought to affect chemicals, called neurotransmitters, in the brain.
Your doctor may have suggested this medication for conditions other than the ones listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. Do not stop taking this medication without consulting your doctor.
Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it.
Is there any reason not to take this drug?
Pizotifen (Sandomigran) should not be taken by anyone who:
- Is allergic to pizotifen or any of the ingredients of the medication
- Is taking monoamine oxidase (MAO) inhibitors
- Is under the age of 12 years
- Has a pyloroduodenal obstruction or stenosing pyloric ulcer
What about possible side effects?
The following side effects have been reported by at least 1% of people taking this medication. Many of these side effects can be managed, and some may go away on their own over time.
Contact your doctor if you experience these side effects that are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.
More common:
- drowsiness
- increased appetite
- weight gain
Less common or rare:
- abdominal discomfort
- confusion
- depression
- dizziness
- dry mouth
- edema (fluid retention)
- fatigue
- headache
- impotence
- low blood pressure
- muscle pain
- nausea
- nervousness
- weakness
Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking this medication.
What if I am taking other drugs?
There may be an interaction between pizotifen (Sandomigran) and any of the following:
- alcohol
- barbiturates (e.g. phenobarbital, butalbital)
- benzodiazepines (e.g. diazepam, lorazepam)
- diabetes medications
- heart disease medications
- sedatives
- sleeping pills
- tricyclic antidepressants (e.g., amitriptyline, desipramine)
If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:
- stop taking one of the medications
- change one of the medications to another
- change how you are taking one or both of the medications
- leave everything as is
An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.
Medications other than those listed above may interact with this medication. Tell your doctor about all prescription, without prescription and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, nicotine or narcotics can affect the action of many medications, you should let your doctor know if you use them.
Other information:
Drowsiness/reduced alertness: Drowsiness may occur with use of pizotifen (Sandomigran) and this may impair your ability to drive or operate machinery. Exercise caution with these activities until you find out whether the medication affects you in this way.
Medical conditions: People with narrow angle glaucoma or with urinary retention (e.g. enlarged prostate) must exercise caution if using this medication. In general, people with narrow-angle glaucoma should not take pizotifen unless it is required and they are under special care and medical supervision for this condition. People with diabetes, heart disease or suspected impaired kidney or liver function should take pizotifen with caution.
Tolerance: With prolonged use of pizotifen (Sandomigran) some people find that it no longer works successfully. If this happens, contact your doctor.
Pregnancy: This medication should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking this medication, contact your doctor immediately.
Special Instructions:
The dose of pizotifen (Sandomigran) is usually started low (0.5 mg at bedtime) and increased gradually to 0.5 mg 3 times daily. The average maintenance dose is 1.5 mg per day. The dose range is 1 mg to 6 mg per day depending on response to the medication. The goal is to reach the lowest dose that best prevents migraine headaches without causing significant side effects. It may take up to 4 weeks for the medication to have its maximum effect.
Your doctor may have you gradually reduce your dosage after having success with it to determine if you still need the medication. Your dose will be reduced gradually to prevent a rebound headache. If your headaches return after you have stopped taking the medication, your doctor may prescribe pizotifen again.
Many things can affect the dose of medication, such as body weight, other medical conditions and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.
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