Buy Zyban, bupropionBuy Zyban to treat depression and to quit smoking. The recommended dose as an aid for smoking cessation is 150 mg daily for 3 days, followed by 150 mg twice daily. You should start taking bupropion at least one week before stopping smoking.Contraindications: Consult a doctor before taking Zyban if you are pregnant or breastfeeding, if you are allergic to any of its ingredients, if you are taking any other medications (especially prochloperazine, chlorpromazine, antipsychotics, benzodiazepines, beta-blockers, carbamazepine, corticosteroids (e.g., prednisone), cyclophosphamide, flecainide, guanfacine, levodopa, lithium, monoamine oxidase inhibitors, orphenadrine, phenytoin, Phenobarbital, propafenone, ritonavir, SSRIs (e.g., paroxetine, sertraline, fluoxetine), theophylline, and tricyclic antidepressants) or if you have or have a history of heart disease, liver disease, seizures, epilepsy, or suicidal thoughts. To read more about Zyban side effects, Zyban dosage, and for more useful information about Zyban (bupropion), please click the product information link below. |
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Other name(s): Aplenzin, Elontril, Zyntabac |
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Often prescribed for major depression, smoking |
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Zyban, bupropionChemical NamesBupropion Ingredients Active ingredients: bupropion Non active: carnauba wax, cysteine hydrochloride, hypromellose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polysorbate 80 and titanium dioxide and is printed with edible black ink Indications Zyban is used to treat depression and cigarette addiction. How It Works Bupropion works by inhibiting the reuptake of dopamine, serotonin, and norepinephrine, an action that results in more dopamine, serotonin, and norepinephrine in the bloodstream to transmit messages to other nerves. Bupropion is unlike other antidepressants in that its major effect is on dopamine, not serotonin. Dosage Available slow-release (SR) tablets: 100 mg, 150 mg, 300 mg The recommended dose as an aid for smoking cessation is 150 mg daily for 3 days, followed by 150 mg twice daily. You should start taking bupropion at least one week before stopping smoking. People with reduced liver or kidney function may require a lower dose. The recommended dosage in the treatment of depression is 150 mg daily, though this can be increased up to a maximum dosage of 450 mg daily. People with reduced liver or kidney function may require a lower dose. Multiple daily doses should be taken at least 8 hours apart. It is very important that bupropion tablets be swallowed whole.
Precautions
Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication. Drowsiness/reduced alertness: People taking bupropion should avoid operating hazardous machinery (including cars) until they are certain that the medication does not impair their mental alertness, judgment, or physical coordination. Heart disease: There is no experience establishing the safety of bupropion for use by people with a recent history of heart attack or unstable heart disease. Liver disease: Because bupropion is cleared from the body through both the liver and the kidney, caution and lower doses should be used by people with liver disease or kidney disease. Bupropion is not recommended for use by people with severe liver disease unless the benefits outweigh the risks. Seizure risk: Bupropion should be used with extreme caution by people who are at increased risk of seizures. Things which increase the risk of seizures include: abrupt withdrawal from alcohol, benzodiazepines, or other sedatives, addiction to cocaine, stimulants, or opiates (such as morphine), diabetes treated with oral medications or insulin, excessive alcohol use, history of head trauma or seizures (including epilepsy), tumours of the the brain or spinal cord, use of other medications that make seizures more likely (e.g., antipsychotics, antidepressants, lithium, theophylline, steroids), use of over-the-counter stimulants or appetite suppressants. Stopping the medication: Stopping this medication suddenly may lead to side effects. If you are thinking of stopping the medication, check with your doctor first. Suicidal or agitated behaviour: Adults and children taking this medication may feel agitated (restless, anxious, aggressive, emotional, and feeling not like themselves), or they may want to hurt themselves or others. These symptoms may occur within several weeks after people start taking this medication. People should be closely monitored by their doctor for emotional and behavioural changes. A study published recently in the New England Journal of Medicine suggests that use of SSRIs during the second half of pregnancy may be associated with a condition called persistent pulmonary hypertension of the newborn. Please speak to doctor if you are preganant or might become pregnant while on Zyban. Drug Interactions Bupropion should be used cautiously in patients receiving drugs that reduce the threshold for seizures. Such drugs include prochlorperazine (Compazine), chlorpromazine (Thorazine), and other antipsychotic medications of the phenothiazine class. Additionally, persons who are withdrawing from benzodiazepines [for example, diazepam (Valium), alprazolam (Xanax)] are at increased risk for seizures. Other drugs that interact are antipsychotics (e.g., haloperidol, risperidone, thioridazine), beta-blockers (e.g., metoprolol), carbamazepine, corticosteroids (e.g., prednisone), cyclophosphamide, flecainide, guanfacine, levodopa, lithium, monoamine oxidase inhibitors (MAO inhibitors; e.g., phenelzine, tranylcypromine, moclobemide), orphenadrine, phenytoin, Phenobarbital, propafenone, ritonavir, SSRIs (e.g., paroxetine, sertraline, fluoxetine), theophylline, and tricyclic antidepressants (e.g., nortriptyline, imipramine, desipramine). There are over 600 medications that interact with Zyban, so if you are taking any medication consult a doctor to see if there is a conflict. Adverse/Side Effects The most commonly observed adverse events consistently associated with the use of Zyban were dry mouth, insomnia, asthenia, fever, headache, dyspepsia, flatulence, vomiting agitation, depression, and irritability, sweating, blurred vision, diplopia, or an increase in the frequency of urination. Contact a doctor if you experience any of the following uncommon side effects: back pain, chills, inguinal hernia, musculoskeletal chest pain, pain, and photosensitivity, flushing, migraine, postural hypotension, stroke, tachycardia, vasodilation, abnormal liver function, bruxism, dysphagia, gastric reflux, gingivitis, glossitis, jaundice, and stomatitis, ecchymosis. anemia, leukocytosis, leukopenia, lymphadenopathy, pancytopenia, thrombocytopenia, edema, increased weight, and peripheral edema, leg cramps and twitching, abnormal coordination, CNS stimulation, confusion, decreased libido, decreased memory, depersonalization, emotional lability, hostility, hyperkinesia, hypertonia, hypesthesia, paresthesia, suicidal ideation, and vertigo. Rare were amnesia, ataxia, derealization, hypomania, aggression, akinesia, aphasia, coma, completed suicide, delirium, delusions, dysarthria, dyskinesia, dystonia, euphoria, extrapyramidal syndrome, hallucinations, hypokinesia, increased libido, manic reaction, neuralgia, neuropathy, paranoid ideation, restlessness, suicide attempt, and unmasking tardive dyskinesia, acne, dry skin, accommodation abnormality and dry eye, deafness, increased intraocular pressure, mydriasis, impotence, polyuria, and urinary urgency. Also observed were abnormal ejaculation, cystitis, dyspareunia, dysuria, gynecomastia, menopause, painful erection, prostate disorder, salpingitis, urinary incontinence, urinary retention, urinary tract disorder, and vaginitis. Contact a doctor immediately if you experience any of these very rare side effects: malaise, syncope, cardiovascular disorder, complete AV block, extrasystoles, hypotension, myocardial infarction, phlebitis, and pulmonary embolism. edema of tongue, colitis, esophagitis, gastrointestinal hemorrhage, gum hemorrhage, hepatitis, increased salivation, intestinal perforation, liver damage, pancreatitis, stomach ulcer, stool abnormality, bronchospasm, pneumonia, maculopapular rash., alopecia, angioedema, exfoliative dermatitis, and hirsutism. Overdose Symptoms of overdose may include seizures, hallucinations, rapid heart rate, and loss of consciousness. In case of overdose please contact your local emergency room or poison control. Storage Instructions Store at controlled room temperature, 20°to 25°C (68°to 77°F) |